“In a PD mouse model the combination of NAC and rhGAA resulted in better correction of enzyme activity in liver, heart, diaphragm and gastrocnemia, compared to rhGAA alone.”
“In cells incubated with NAC and rhGAA , GAA activities were 3.7-8.7-fold higher than those obtained in cells treated with rhGAA alone.”
“ NAC also enhanced rhGAA efficacy in PD fibroblasts.”
“ NAC improved the stability of rhGAA as a function of pH and temperature without disrupting its catalytic activity.”