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Discover Supplement-Drug Interactions

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Last Updated: 4 years ago

Possible Interaction: Acetylcysteine and Thrombin Alfa

Research Papers that Mention the Interaction

In a PD mouse model the combination of NAC and rhGAA resulted in better correction of enzyme activity in liver, heart, diaphragm and gastrocnemia, compared to rhGAA alone.
In cells incubated with NAC and rhGAA , GAA activities were 3.7-8.7-fold higher than those obtained in cells treated with rhGAA alone.
NAC also enhanced rhGAA efficacy in PD fibroblasts.
NAC improved the stability of rhGAA as a function of pH and temperature without disrupting its catalytic activity.
Molecular therapy : the journal of the American Society of Gene Therapy  •  2012  |  View Paper
NAC treatment … by rk-2 and down-regulated p53 and nuclear p21Waf1/Cip1 expression induced by rk-2.These data suggest that rk-2 induces the BCE …–G1 phase through inhibition of the cyclin D1/CDK4 complex caused by increase of ROS generation and nuclear cyclin-dependent kinase inhibitors.
Angiogenesis  •  2005  |  View Paper