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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Acetylcysteine and Tamoxifen



Research Papers that Mention the Interaction

Treatment with the antioxidant N-acetyl-l-cysteine (NAC) blunted the increase in Zn2+ levels and reduced LC3-II conversion, cathepsin D release and cell death induced by tamoxifen.
BioMetals  •  2010  |  View Paper
An antioxidant, N-acetylcysteine significantly inhibited both ROS production and apoptosis induced by TAM , suggesting that ROS may play an essential role in the TAM-induced apoptosis.
Cell Death and Differentiation  •  2000  |  View Paper
Administration … TAM prevented increased urinary sodium excretion as … as attenuated the downregulation of βENaC and γENaC. Consistent with these findings, immunohistochemistry (IHC) showed stronger labeling of βENaC and γENaC subunits in the … domain of the collecting duct cells in the cortical tissue of lithium-fed rats treated with TAM.
Front. Physiol.  •  2018  |  View Paper