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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcysteine
drug:
Sulfasalazine
Research Papers that Mention the Interaction
“Whereas acute systemic treatment with sulfasalazine lowered the threshold for Aß to interfere with synaptic plasticity, N‐acetylcysteine prevented the inhibition of LTP by Aß alone or in combination with sulfasalazine.”
Opposite in vivo effects of agents that stimulate or inhibit the glutamate/cysteine exchanger system xc− on the inhibition of hippocampal LTP by Aß“It was also showed SSZ could attenuate ACLT + MMx‐induced cartilage destruction, and treatment of NAC reversed the protective effect of SSZ.”
“The intra‐articular injection of SSZ significantly attenuated knee swelling and cartilage destruction in the knees of ACLT + MMx rats and this effect was blocked by NAC.”
“Daily intraperitoneal administration of NAC (250 and 500 mg/kg/day) and/or DTT (15 and 30 mg/kg/day) effectively alleviated renal damage induced by sulfasalazine.”
“The inhibitory effect of N-acetylcysteine on chronic nicotine intake was blocked by the administration of sulfasalazine , an inhibitor of the xCT transporter.”
Administration of N-acetylcysteine Plus Acetylsalicylic Acid Markedly Inhibits Nicotine Reinstatement Following Chronic Oral Nicotine Intake in Female Rats
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