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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Acetylcysteine
drug:
Streptozocin
Research Papers that Mention the Interaction
“Moreover, NAC attenuated the inhibition of mitochondrial functions induced by STZ through partial recovery of the mitochondrial enzymes and restoration of membrane potential.”
Cytoprotective Effects of N-Acetylcysteine on Streptozotocin- Induced Oxidative Stress and Apoptosis in RIN-5F Pancreatic β-Cells“In conclusion, NAC treatment prevented the cognitive impairment induced by STZ , normalizing the AChE activity and rescuing the synaptic plasticity loss.”
“The increase in AChE activity and decrease in pTrkB and MnSOD levels caused by STZ in the cerebral cortex and hippocampus, were prevented by the NAC and PHY treatments.”
“Brain cortex and hippocampus AChE and hippocampus BChE activities increase induced by STZ were also prevented by NAC treatment.”
“ N-acetylcysteine and pentoxifylline, free radical scavengers and inhibitors of tumor necrosis factor-alpha (TNF-alpha) production, inhibit the development of peripheral neuropathy in streptozotocin (STZ)-induced diabetic rats.”
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