“Conclusions: As premedication of gastroscopy, simethicone plus NAC offers more benefit on positive findings and total mucosal visibility score.”
“ Simethicone plus NAC showed better total mucosal visibility score than simethicone alone (MD = −0.14 (−0.25, −0.03), P = 0.01) without obvious heterogeneity.”
“The rate of positive findings in simethicone plus NAC group was higher than that in water group (risk ratio [RR] =1.31, 95%CI: 1.12–1.53, P = 0.0006) with high level of evidence.”