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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Acetylcysteine and Simethicone

Research Papers that Mention the Interaction

Group A: water; Group B: water with simethicone; Group C: water with simethicone plus NAC 600 mg; Group D: water with simethicone, NAC, sodium bicarbonate and peppermint.
Surgical Endoscopy  •  2020  |  View Paper
Conclusions: As premedication of gastroscopy, simethicone plus NAC offers more benefit on positive findings and total mucosal visibility score.
Simethicone plus NAC showed better total mucosal visibility score than simethicone alone (MD = −0.14 (−0.25, −0.03), P = 0.01) without obvious heterogeneity.
The rate of positive findings in simethicone plus NAC group was higher than that in water group (risk ratio [RR] =1.31, 95%CI: 1.12–1.53, P = 0.0006) with high level of evidence.
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association  •  2019  |  View Paper