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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcysteine
drug:
Salicylic Acid
Research Papers that Mention the Interaction
“However, there was a substantial reduction in the mean OHC loss of the NAC plus 50 or 75 mg/kg (but not the 25 mg/kg) SAL groups.”
Dosing study on the effectiveness of salicylate/N-acetylcysteine for prevention of noise-induced hearing loss.“Treatment with acetylcysteine and salicylate given concomitantly resulted in an anti-inflammatory response which was equal to that obtained with thiosalicylate and was significantly greater than that obtained with either acetylcysteine or salicylate given individually.”
“In addition, compounds that scavenge ROS N-acetylcysteine , glutathione, catalase and superoxide dismutase) reverse the increased UVC survival induced by growth in the presence of salicylate , while ROS donors (tert-butylhydroperoxide, H2O2 and NaClO) enhance survival of salicylate challenged cultures.”
Salicylate induces reactive oxygen species and reduces ultraviolet C susceptibility in Staphylococcus aureus“These NAC TFs exert this inhibitory effect by repressing ICS1 and activating BSMT1, genes involved in SA biosynthesis and metabolism, respectively.”
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