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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcysteine
supplement:
Resveratrol
Research Papers that Mention the Interaction
“Cells were treated with resveratrol either alone or combined with NAC 10-100-1000 μM. There was a dose-related increase in the rate of cell proliferation and in inhibition of collagenase activity.”
[Efficacy study in vitro: assessment of the properties of resveratrol and resveratrol + N-acetyl-cysteine on proliferation and inhibition of collagen activity].“Inhibition of ∆Ψm breakdown and of ROS generation by N‐acetylcysteine , or by overexpression of Bcl‐2 protein, prevented apoptosis induction by resveratrol.”
“Co‐administration of resveratrol and NAC reduces the ototoxic secondary effects by aminoglycosides.”
“Results indicate that administration of resveratrol plus N‐acetylcysteine reduced the threshold shifts induced by ototoxic drugs at high frequencies (≈10 dB), although this protective effect fades after the cessation of the treatment.”
“Thus, co‐administration of resveratrol and NAC , routinely used individually in patients, could reduce the ototoxic secondary effects of aminoglycosides.”
The expression of oxidative stress response genes is modulated by a combination of resveratrol and N-acetylcysteine to ameliorate ototoxicity in the rat cochlea“In addition, we observed that RSV can act additively to both NAC and paraquat, to dramatically increase lifespan.”
“The combination of NAC , ascorbic acid, and resveratrol , each at much lower concentrations, had a synergistic protective effect.”
“Two dietary supplements, N-acetylcysteine and resveratrol , complement each other in reducing formation of catechol estrogen-3,4-quinones and inhibiting formation of estrogen-DNA adducts in cultured human and mouse breast epithelial cells.”
Etiology and prevention of prevalent types of cancer
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