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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcysteine
drug:
Propyl Gallate
Research Papers that Mention the Interaction
“The treatment with antioxidant of N-acetyl-cysteine (NAC) or ascorbate acid (AA) prevented CPAEC growth inhibition and death by PG , which was accompanied by the attenuation of GSH depletion but not by the reduction of ROS level.”
Propyl gallate inhibits the growth of calf pulmonary arterial endothelial cells via glutathione depletion.“In contrast, the pretreatment of N-acetylcysteine (4 mM), a precursor of intracellular glutathione (GSH) and antioxidant, prevented PG (0.5 mM)-induced formation of soluble DNA fragments and loss of cellular GSH, ATP, and formation of blebbing.”
Propyl gallate-induced DNA fragmentation in isolated rat hepatocytes“ NAC decreased the ROS levels in the H2O2-treated HPFs and PG markedly prevented an increase in O2•− levels in these cells.”
Effects of antioxidants and MAPK inhibitors on cell death and reactive oxygen species levels in H2O2-treated human pulmonary fibroblasts
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