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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcysteine
drug:
Prednisolone
Research Papers that Mention the Interaction
“In SAH, NAC combined with prednisolone resulted in a one-month death rate 1/3 of that of patients given only prednisone (8% vs 24%, P = 0.006) [7].”
Know When to Hold ‘em, Know When to Treat ‘em, Know When to Cut ‘em: Why Severe Alcoholic Hepatitis Is Becoming a Surgical Disease“The effects of prednisolone on apoptosis and mtROS were blocked 1) by the glucocorticoid receptor (GR) antagonist RU-38486, 2) in cells with GR siRNA knockdown, and 3) by treatment with N-acetylcysteine.”
“The inclusion of this faux placebo lead some, possibly correctly, to suggest that NAC was inhibiting the adverse effects of prednisolone and azathioprine, rather than possessing any direct antifibrotic effect.”
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