supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Acetylcysteine
drug:
Pimagedine
Research Papers that Mention the Interaction
“Conversely, pretreatment with N-acetylcysteine , a ROS scavenger, and aminoguanidine , an MGO blocker, prevented MGO-induced growth retardation.”
Methylglyoxal, a reactive glucose metabolite, enhances autophagy flux and suppresses proliferation of human retinal pigment epithelial ARPE-19 cells.“These effects of D-ribose seemed almost irreversible but could be prevented by addition of 1 mM aminoguanidine or 10 mM N-acetylcysteine , thus suggesting that glycation and reactive oxygen species, generated through the glycation reaction, serve as mediators of the phenomena.”
“ N-Acetyl-L-cysteine , an antioxidant, and aminoguanidine , an inhibitor of the glycation reaction, inhibited this apoptosis.”
Reducing sugars trigger oxidative modification and apoptosis in pancreatic beta-cells by provoking oxidative stress through the glycation reaction.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback