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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Acetylcysteine and Penicillins

Research Papers that Mention the Interaction

With other antibiotics, 10 mM NAC had no major effects, while 50 mM NAC sporadically decreased (ceftriaxone and aminoglycosides) or increased ( penicillins ) antibiotic activity.
Antimicrobial Agents and Chemotherapy  •  2016  |  View Paper
Acetylcysteine seems to be rapidly inactivated by high concentrations of oxygen and itself probably antagonises some penicillins and tetracyclines in sputum.2 The makers now recommend that compressed air, and not oxygen, should be used for nebulisation.
Drug and therapeutics bulletin  •  1966  |  View Paper
The presence of 10 mM NAC reduced the MIC of penicillin , ampicillin, oxacillin, cefoxitin, ceftazidime, and cefotaxime to MRSA.
Journal of dairy science  •  2019  |  View Paper
The presence of 10mM NAC reduced the MIC of penicillin and ampicillin but enhanced the MIC of erythromycin and ciprofloxacin for all of the strains.
Journal of dairy science  •  2016  |  View Paper