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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcysteine
drug:
Parthenolide
Research Papers that Mention the Interaction
“Pretreatment with N-acetyl-cysteine abrogated the increased sensitivity of RIP3-transfected MCF-7 and MDA-MB-231 cells to parthenolide.”
RIP3 overexpression sensitizes human breast cancer cells to parthenolide in vitro via intracellular ROS accumulation“The effects of Bay 11-7082 and parthenolide on annexin V binding could be fully reversed by the antioxidant N-acetylcysteine.”
“In the present study, induction of apoptosis by parthenolide and BAY 11-7085, drugs that targeted nuclear factor kappa B activation, was blocked by the presence of N-acetylcysteine (NAC).”
Implications of the involvement of the endoplasmic reticulum stress pathway in drug-induced apoptosis.“Pretreatment with the antioxidant, N‐acetyl‐L‐cysteine , completely suppressed the effect of parthenolide on JAK1 and STAT3.”
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