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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcysteine
Research Papers that Mention the Interaction
“TGFbeta3 mRNA level was markedly reduced by LPS alone, or with both L-NMMA and NAC.”
Expression of TGF-betas and their receptors is differentially modulated by reactive oxygen species and nitric oxide in human articular chondrocytes.“We investigated whether co-administration of N-acetylcysteine (NAC, a scavenger for reactive oxygen species) and NG-monomethyl-l-arginine (L-NMMA, a non-selective nitric oxide synthase inhibitor) results in better hemodynamic recovery.”
Post-resuscitation NOS inhibition does not improve hemodynamic recovery of hypoxic newborn pigs“Pre-treatment with L-mono-methyl-arginine and N-acetyl-cysteine in oxidized low-density lipoprotein (ox-LDL) exposed HA cells, inhibited not only nitrite but also superoxide production suggesting that (O−2) anion could partially derive from inducible NO synthase.”
“As both, N-acetylcysteine , a GSH precursor, and N(G)-monomethyl-L-arginine , a NO synthase inhibitor, totally inhibited the elevation of LMW iron and oxidative stress, a cooperative role could be attributed to NO production and GSH depletion.”
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