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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcysteine
drug:
Methotrexate
Research Papers that Mention the Interaction
“The inhibitory effect of N‐acetyl cysteine to reverse the acquired MTX resistance was greater than that of the iron chelator, deferasirox, highlighting the importance of iron‐mediated ROS in MTX resistance.”
Iron protects childhood acute lymphoblastic leukemia cells from methotrexate cytotoxicity“These data indicate that NAC may be of therapeutic use in preventing hepatotoxicity in patients receiving MTX treatment.”
N-acetylcysteine ameliorates methotrexate-induced oxidative liver damage in rats.
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