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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcysteine
supplement:
Mechlorethamine
Research Papers that Mention the Interaction
“ HN2 exposure induced increased reactive oxygen species (ROS) formation and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity in NHBECs, findings that were inhibited by NAC and DPI treatment.”
Role of nicotinamide adenine dinucleotide phosphate oxidase in mediating vesicant-induced interleukin-6 secretion in human airway epithelial cells.“Only N-acetylcysteine , however, was found to prevent cell death induced by HN2 , though it must be present at the time of the HN2 challenge.”
“PARP inhibitors (niacinamide, 3-aminobenzamide, 6(5H)-phenanthridinone), and two sulfhydryl-group donors N-acetylcysteine , WR-1065) were found to be effective in preventing HN2-induced metabolic dysfunction when added in immediate or delayed treatment with HN2.”
“This protective effect will still obtained when NAC was added 30 min after HN2.”
N-acetylcysteine protects lymphocytes from nitrogen mustard-induced apoptosis.
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