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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcysteine
drug:
Isoflurane
Research Papers that Mention the Interaction
“ N-acetylcysteine applied during isoflurane treatment restored APC in T2DNmtFHH (39 ± 6%, n = 7; and 38 ± 5%, n = 7; 150 and 75 mg/kg N-acetylcysteine, respectively), but abolished protection in control rats (54 ± 8%, n = 6).”
Cardioprotection during Diabetes: The Role of Mitochondrial DNA“The creatinine levels were reduced in animals pretreated with inhaled isoflurane and NAC , and the level was more significantly decreased in the isoflurane-treated group.”
“… isoflurane … N-acetyl-l-cysteine decreased the sensitization effect by isoflurane in a concentration-dependent manner, whereby the densities of IKATP were 32.6 ± 1.4 (n = … = 6), and 19.4 ± 2.1 pA/pF (n = 8) at 100, 250, and 500 &mgr;m N-acetyl-l-cysteine, respectively.”
“Chelerythrine, rottlerin, PKC-&egr;V1–2 …, lavendustin A, PP1, 5-hydroxydecanote, and N-acetylcysteine abolished the anti-… actions of isoflurane (58 ± 2% [n = 8], 50 ± 3% [n = 9], 53 ± 2% [n = 9], 59 ± 3% [n = …], 57 ± 3% [n = 7], 60 ± 3% [n = 7], and 53 ± 3% [n = 6], respectively).”
“ Isoflurane with NAC has lesser effect on liver function tests compared to isoflurane alone.”
The effects of N-acetylcysteine on hepatic function during isoflurane anaesthesia for laparoscopic surgery patients
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