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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcysteine
drug:
Indomethacin
Research Papers that Mention the Interaction
“The apoptotic effect of indomethacin was then confirmed by fluorescent staining of the cells with annexin V. Apoptotic DNA fragmentation induced by indomethacin and flurbiprofen was suppressed by incubation of the cells with the anti-oxidants pyrrolidine dithiocarbamate, diphenyleneiodonium chloride, and N-acetyl-L-cysteine.”
Reactive oxygen species are involved in the apoptosis induced by nonsteroidal anti-inflammatory drugs in cultured gastric cells.“In the groups that received A/A , either alone or combined with indomethacin , an inhibition of bone growth, both in thickness and in length was demonstrated.”
Free radical scavengers are more effective than indomethacin in the prevention of experimentally induced heterotopic ossification“We found that indomethacin induced an increase in villous perfusion that was significantly reduced by N-acetylcysteine , indicating that superoxide and its precursors may participate in the regulation of blood supply to the mucosa in this animal model of intestinal inflammation.”
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