Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 months ago

Possible Interaction: Acetylcysteine and Hyaluronoglucosaminidase

Research Papers that Mention the Interaction

In addition, we found that hypoxia increased ROS production and that ROS inhibitors NAC ) blocked GLI1-dependent EMT process and invasion under hypoxic conditions.
Cellular Physiology and Biochemistry  •  2017  |  View Paper
Furthermore, antioxidant N-acetyl cysteine , PEG-catalase, and mito-TEMPO effectively inhibited cell migration and invasion in these clones.
PloS one  •  2013  |  View Paper
Pretreatment of the cells with N-acetyl-L-cysteine (NAC) significantly prevented suppression of MMPs and uPA secretion, DNA binding activity of NF-kappaB, and in vitro invasion of HT1080 cells by As2O3, suggesting a role of reactive oxygen species (ROS) in this process.
Journal of cellular biochemistry  •  2005  |  View Paper
We demonstrated that N-acetyl-l-cysteine is able to reduce the invasive and metastatic potential of melanoma cells, and to inhibit endothelial cell invasion by direct inhibition of MMP activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology  •  2002  |  View Paper
NAC inhibited TPA-enhanced invasion dose-dependently.
Anticancer research  •  2001  |  View Paper
NAC also inhibits invasion and metastasis of malignant cells, as well as tumor take.
Anticancer research  •  2000  |  View Paper
Attenuation of ROS production with N-acetylcysteine abolishes AK4-induced invasion potential under hypoxia.
Journal of Hematology & Oncology  •  2019  |  View Paper
Both sulforaphane-cysteine (SFN-Cys) and sulforaphane-N-acetyl-l-cysteine (SFN-NAC) inhibited cancer migration and invasion , but the underlying mechanisms were not clear.
Combined with the inhibitor of autolysosome formation, Bafilomycin A1 (100 nM), SFN-NAC inhibited invasion via accumulating LC3 II and blocking formation of autolysosome.
Cell Death & Disease  •  2019  |  View Paper
NAC (ROS scavenging agent) could inhibit the migration and invasion through reversing EMT and decrease the expression of HO-1.
American journal of cancer research  •  2016  |  View Paper
N-acetylcysteine NAC ), a ROS scavenger, decreased both the levels of intracellular ROS and invasion of F. nucleatum into HOK-16B cells, confirming the role of ROS in bacterial invasion.
Journal of periodontal & implant science  •  2014  |  View Paper
Show More