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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Acetylcysteine and Hemin

supplement:

Acetylcysteine

drug:

Hemin

Research Papers that Mention the Interaction

NAC inhibited the intracellular accumulation of hemin and prevented hemin-induced cell growth inhibition, cell death, oxidative stress, and accumulation of ubiquitinated proteins.
European journal of pharmacology  •  2020  |  View Paper
EDTA, N‐acetylcystein and glutathione prevented the toxicity of hemin and hemin/MAA.
Biochemical pharmacology  •  2019  |  View Paper
Both NAC and AA eliminated transient increased ROS levels after hemin treatment, inhibited hemin-induced hemoglobin synthesis, and decreased mRNA expression levels of β-globin, γ-globin, and GATA-1 genes significantly.
Biomedical and environmental sciences : BES  •  2018  |  View Paper
Albumin decreased and N-acetylcysteine (NAC) both prevented and reversed rigidity induced by hemin.
The American journal of tropical medicine and hygiene  •  2007  |  View Paper
Hemin induced significant increase in reactive oxygen species (ROS) production and hemin‐induced angiogenic response of EPCs was substantially reduced by treatment with N‐acetylcysteine.
Journal of cellular physiology  •  2009  |  View Paper
The anti‐tumour effect of haemin and IL‐2 was enhanced (63% decrease in metastases) by administration of the thiol compound, N‐acetylcysteine.
Clinical and experimental immunology  •  1993  |  View Paper