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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Acetylcysteine and Gentamicin

supplement:

Acetylcysteine

Research Papers that Mention the Interaction

However, NAC antagonized the activity of gentamicin and tobramycin.
Journal of clinical microbiology  •  1977  |  View Paper
Interactions observed for NAC and gentamicin were synergistic (4.5%), indifferent (45.5%) or antagonistic (50%).
Veterinary dermatology  •  2019  |  View Paper
Caspase activity in organ of Corti was significantly reduced by combined treatment with 11R-VIVIT + N-acetylcysteine + gentamicin , compared to 11R-VIVIT + gentamicin or gentamicin alone.
Journal of neurochemistry  •  2019  |  View Paper
These data show that the protective effects of NAC might be related, at least in part, to a reduced inflammatory response, as observed in animals treated with both gentamicin and NAC.
Shock  •  2019  |  View Paper
The group that received NAC in addition to gentamicin had better ABR thresholds and better OAEs.
The journal of international advanced otology  •  2015  |  View Paper
The concentration of GM in the renal cortex of the rats given GM + NAC (but not TMP) was lower than that found in rats treated with GM alone by about 25%.
Journal of applied toxicology : JAT  •  2009  |  View Paper
With the addition of N-acetylcysteine into the “ gentamicin + bone cement” and “vancomycin + bone cement” mixtures, a significant decrease in mechanical fatigue resistance was observed both on day 1 and day 15 (p < 0.001).
Journal of Orthopaedic Surgery and Research  •  2018  |  View Paper