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Last Updated: 3 years ago

Possible Interaction: Acetylcysteine and Fenretinide

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supplement:

Acetylcysteine

drug:

Fenretinide

Research Papers that Mention the Interaction

“The antioxidant N-acetylcysteine decreased GSK3β phosphorylation and poly(ADP-ribose) polymerase cleavage induced by 4HPR , As2O3, and PEITC, implicating oxidative stress in these effects.”

Glycogen Synthase Kinase 3 Regulates Cell Death and Survival Signaling in Tumor Cells under Redox Stress1

Neoplasia • 2014 | View Paper

“ HPR treatment also induced a 10-fold increase (P = 0.02) in the sub-G0 (apoptotic) peak that was down-regulated in the presence of the antioxidant N-acetyl-L-cysteine.”

Inhibition of aberrant proliferation and induction of apoptosis in HER-2/neu oncogene transformed human mammary epithelial cells by N-(4-hydroxyphenyl)retinamide.

Carcinogenesis • 1999 | View Paper

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