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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Acetylcysteine and Emodin

supplement:

Acetylcysteine

supplement:

Emodin

Research Papers that Mention the Interaction

Pretreatment with the antioxidant NAC diminished apoptosis and p53 overexpression induced by emodin.
Asian Pacific journal of cancer prevention : APJCP  •  2014  |  View Paper
…,emodin significantly increased the levels of ROS and MDA, inhibited both SOD level … ratio in human T cells, whereas co-incubation with the ROS scavenger N-acetylcysteine (NAC, 20 μmol/L) almost completely blocked emodin-induced ER stress … in human T cells, and decreased the caspase cascade-mediated apoptosis.
Acta Pharmacologica Sinica  •  2013  |  View Paper
Exposure of SA-NH and FSa tumor cells to 10mM NAC inhibited the ability of 5mGy and Emodin to induce intracellular translocation of survivin and the corresponding altered adaptive survival response.
Free radical biology & medicine  •  2016  |  View Paper
The ROS scavenger NAC , p38 silencing and Puma silencing impaired the anti-proliferation and apoptosis- inducing effects of emodin.
International journal of clinical and experimental medicine  •  2015  |  View Paper