“Clotrimazole, a specific inhibitor of the Ca2+ activated potassium (Gardos) channel, and the antioxidant N‐acetylcysteine were found to inhibit the in vitro formation of high‐density sickle cells induced by treatment with 1‐chloro‐2,4‐dinitrobenzene (CDNB).”
“The CDNB induced leakage of K+ can be inhibited by treatment of SS erythrocytes with 20 mM N‐acetylcysteine.”