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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcysteine
supplement:
Diallyl Disulfide
Research Papers that Mention the Interaction
“Scavenging of DADS‐induced ROS by N‐acetyl cysteine or reduced glutathione inhibited cell cycle arrest, apoptosis and p53 activation by DADS.”
Molecular mechanism of diallyl disulfide in cell cycle arrest and apoptosis in HCT‐116 colon cancer cells“A combination of DADS and NAC completely prevented cataractogenesis, and all of the treated animals survived APAP toxicity.”
“Assay of plasma glutamate-pyruvate transaminase activity, an indicator of liver necrosis, showed that treatment with DADS and NAC together effectively protected the liver.”
“At 4 hours after APAP injection, hepatic GSH began to increase only when DADS and NAC were administered together.”
Prevention of acetaminophen-induced cataract by a combination of diallyl disulfide and N-acetylcysteine.“In vitro assay indicates that DADS,but not NAC,was a potent inhibitor of ERD activity(IC(50) = 4.6&mgr;m).CONCLUSION:A combined use of both DADS and NAC produced full protection in BNF treated mice against APAP hepatotoxicity.”
Effects of combined use of diallyl disulfide and Nacetyl-cysteine on acetaminophen hepatotoxicity in beta-naphthoflavone pretreated mice.
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