supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Acetylcysteine
drug:
Darusentan
Research Papers that Mention the Interaction
“In aged rats, darusentan treatment increased ion excretion (P<0.05), reduced cortical gene expression of αENaC and α1-Na+, K+-ATPase (both P<0.05), and increased plasma aldosterone levels (P<0.01).”
“Treatment with darusentan also reduced cortical expression of αENaC and α1-Na+, K+-ATPase and increased plasma aldosterone levels independently of blood pressure, electrolytes, renin activity, or angiotensin converting enzyme activity.”
Endothelin ETA Receptor Blockade With Darusentan Increases Sodium and Potassium Excretion in Aging Rats
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback