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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcysteine
supplement:
Cobalt
Research Papers that Mention the Interaction
“Furthermore, wortmannin, LY294002, and N-acetyl-L-cysteine inhibit the effect of cobalt , suggesting that it involves the phosphatidylinositol 3 kinase pathway and production of reactive oxygen species.”
Cobalt induces hypoxia-inducible factor-1alpha expression in airway smooth muscle cells by a reactive oxygen species- and PI3K-dependent mechanism.“The concentration of cobalt in the various tissues was only decreased by NAC (liver and spleen) and glutathione (spleen).”
“ N-acetyl-cysteine may provide chelating sites for metals and in our cases reduced Co and Cr blood levels and resulted well tolerable.”
N-Acetyl-Cysteine as Effective and Safe Chelating Agent in Metal-on-Metal Hip-Implanted Patients: Two Cases
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