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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcysteine
supplement:
Butyric Acid
Research Papers that Mention the Interaction
“The combination of PBA and NAC pretreatment could further prevent TDCIPP induced ER‐stress and apoptotic death compared with PBA or NAC pretreatment alone.”
Tris (1,3‐dichloro‐2‐propyl) phosphate‐induced apoptotic signaling pathways in SH‐SY5Y neuroblastoma cells“However, the decrease in cFLIP expression by butyric acid was not restored by treatment with NAC; increases in caspase-4 and -10 activities by butyric acid were completely abrogated by NAC.”
“ NAC also affected the elevation of GRP78 and CHOP/GADD153 expression by butyric acid.”
“Pretreatment of cells with the antioxidant N-acetyl-cysteine or 3-aminobenzamide attenuated butyric acid-induced apoptosis through a reduction of ROS generation.”
“Additionally, supplementation of butanoic acid- and pentanoic acid-treated cultures with N-acetyl cysteine (NAC) reduced the population of cells entering early apoptosis by 5.3 and 10.0%, respectively, while increasing productivity by 19.5% in the presence of pentanoic acid and NAC.”
“Conversely, a decrease of 5.7% in production was observed in response to combined butanoic acid and N-acetyl cysteine treatment.”
Enhanced production of recombinant proteins by a small molecule protein synthesis enhancer in combination with an antioxidant in recombinant Chinese hamster ovary cells
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