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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Acetylcysteine and Bradykinin



Research Papers that Mention the Interaction

BK (10 nM) increased VSMC proliferation by 30% (n=5); this proliferation was inhibited by the antioxidants N-acetylcysteine (20 mM) and alpha-lipoic acid (LA, 250 mM).
Biological research  •  2004  |  View Paper
Preincubation of VSMCs with either N-acetyl-L-cysteine and/or alpha-lipoic acid significantly decreased bradykinin-induced cytosolic and nuclear phosphorylation of p42(mapk) and p44(mapk).
Hypertension  •  2000  |  View Paper
Additional experiments supported the hypothesis that n-acetylcysteine is an oxygen radical scavenger, since it reduced or prevented the free radical-dependent cerebral arteriolar dilation normally induced by the topical application of arachidonic acid or bradykinin.
Journal of neurosurgery  •  1991  |  View Paper
BK transiently decreased human RPE (ARPE-19) cell monolayer resistance, and this effect was blocked by vasoinhibins, L-NAME, and NAC.
Front. Cell. Neurosci.  •  2014  |  View Paper