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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Acetylcysteine and Bismuth Subsalicylate

Research Papers that Mention the Interaction

Suppressing either oxidative stress or ER stress was protective against light damage in 661W and ARPE-19 cells and N-acetyl-L-cysteine treatment markedly inhibited the activation of ER stress caused by light exposure.
Aging  •  2020  |  View Paper
In addition, inhibition of reactive oxygen species using N-acetylcysteine attenuated ER stress , expression of osteoclast-specific marker genes, and RANKL-induced CREBH activation.
The Journal of Immunology  •  2018  |  View Paper
N-acetylcysteine , a ROS scavenger, diminished ER stress and autophagy induction effects.
Scientific Reports  •  2018  |  View Paper
ER stress and apoptosis caused by TDZ were prevented by ROS inhibitor N-acetyl-L-cysteine ( NAC ) and protein synthesis inhibitor cycloheximide.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie  •  2018  |  View Paper
Furthermore, blocking ROS with NAC inhibited SW-induced ER stress , as evidenced by the downregulation of GRP78, phosphorylated (p)-protein kinase R-like ER kinase (PERK), p-inositol-requiring kinase 1α (IRE1α), p-50 activating transcription factor 6α and CHOP.
International journal of molecular medicine  •  2018  |  View Paper
Consistently, our data revealed as well that mitigation of intracellular ROS levels with antioxidant NAC markedly attenuated H2O2-induced AMPK activation and ER stress.
International journal of medical sciences  •  2018  |  View Paper
N-acetylcysteine and 4-phenylbutyric acid inhibited NPPB-induced oxidative stress, ER stress and apoptosis.
International journal of molecular medicine  •  2021  |  View Paper
Meanwhile, the activation of the NF-E2-related factor-2 (NRF2)-driven stress gene activation, a key element involved in HIC, was suppressed by NAC.
European journal of pharmacology  •  2020  |  View Paper
Pre-treatment with NAC , a ROS production inhibitor, significantly reduced ER stress and apoptosis-related proteins induced by PD.
Cellular Physiology and Biochemistry  •  2018  |  View Paper
Furthermore, costunolide induced ROS generation, while the antioxidant N‐acetyl cysteine (NAC) effectively blocked ER stress and apoptosis activation, suggesting that ROS acts as an upstream signaling molecule in triggering ER stress and mitochondrial apoptotic pathways.
Cell biology international  •  2016  |  View Paper
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