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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Acetylcysteine and Auranofin

supplement:

Acetylcysteine

Research Papers that Mention the Interaction

In cell culture, auranofin inhibited growth in a dose-dependent manner, and N-acetyl-L-cysteine (NAC), a scavenger of reactive oxygen species (ROS), markedly blocked the effect of auranofin.
BMB reports  •  2013  |  View Paper
Pre-treatment with N-acetyl cysteine , a well-known scavenger of reactive oxygen species, but not with a chemical chaperone, which inhibits endoplasmic reticulum stress and the ensuing unfolded protein response, significantly reduced the radiosensitizing effects of auranofin in the IEC-6 cells.
Front. Pharmacol.  •  2019  |  View Paper
Au , BSO and radiation also significantly decreased breast cancer cell migration and invasion in a thiol-dependent manner that could be inhibited by NAC.
Radiation Research  •  2016  |  View Paper
Incubation of cysticerci in the presence of both AF and N-acetyl cysteine ( NAC ) prevents all the above changes, maintaining cysticerci viability.
Molecular and biochemical parasitology  •  2015  |  View Paper