Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Acetylcysteine and Apigenin

supplement:

Acetylcysteine

supplement:

Apigenin

Research Papers that Mention the Interaction

Apigenin induced ROS production in the L. amazonensis-infected macrophage, and the effects were reversed by NAC and GSH.
PLoS neglected tropical diseases  •  2016  |  View Paper
As we presumed, treatment with apigenin was found to increase the level of intracellular reactive oxygen species (ROS), whereas pretreatment with antioxidants, N-acetyl-cysteine (NAC) or glutathione (GSH), completely attenuated ROS generation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association  •  2012  |  View Paper
In addition, N-acetylcysteine reduced ROS production and improved ΔΨm loss and cell death that were caused by apigenin.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology  •  2020  |  View Paper
The pro-apoptotic effect of apigenin was counteracted by RR and NAC pretreatment.
Journal of ethnopharmacology  •  2019  |  View Paper