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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Acetylcysteine
drug:
Allopurinol
Research Papers that Mention the Interaction
“This effect was partially reversible by treatment with the antioxidant N‐acetyl cysteine and allopurinol.”
Hypoxanthine induces cholesterol accumulation and incites atherosclerosis in apolipoprotein E‐deficient mice and cells“Addition of N-acetylcysteine and allopurinol together caused nearly complete cytoprotection against AZA-induced hepatocyte death.”
“N-Acetylcysteine NAC ) and allopurinol (ALP) synergistically reduce myocardial ischemia reperfusion (MI/R) injury in diabetes.”
“ConclusionsThis study offers that combined use of N-acetylcysteine and allopurinol might help protect the spinal cord against ischemia/reperfusion injury.”
Effect of N-acetylcysteine and allopurinol combination to protect spinal cord ischemia/reperfusion injury induced by aortic cross-clamping in rat model“ ALP enhanced the effects of NAC in restoring cardiac AdipoR2 and phosphorylation of Akt, STAT3 and eNOS in diabetic rats.”
“Conclusions/Significance NAC and ALP synergistically restore myocardial APN and AdipoR2 mediated eNOS activation.”
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