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Discover Supplement-Drug Interactions

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Last Updated: a month ago

Possible Interaction: Acetylcysteine and Allopurinol

Research Papers that Mention the Interaction

This effect was partially reversible by treatment with the antioxidant N-acetyl cysteine and allopurinol.
Journal of cellular and molecular medicine  •  2016  |  View Paper
Addition of N-acetylcysteine and allopurinol together caused nearly complete cytoprotection against AZA-induced hepatocyte death.
BioMed research international  •  2014  |  View Paper
N-Acetylcysteine NAC ) and allopurinol (ALP) synergistically reduce myocardial ischemia reperfusion (MI/R) injury in diabetes.
Free radical biology & medicine  •  2013  |  View Paper
ConclusionsThis study offers that combined use of N-acetylcysteine and allopurinol might help protect the spinal cord against ischemia/reperfusion injury.
Journal of Cardiothoracic Surgery  •  2015  |  View Paper
CONCLUSION NAC and ALP confer synergistic cardioprotection in diabetes via restoration of cardiac HIF-1α and HO-1 signaling.
CONCLUSION NAC and ALP confer synergistic cardioprotection in diabetes via restoration of cardiac HIF-1α and HO-1 signaling.
PloS one  •  2013  |  View Paper
ALP enhanced the effects of NAC in restoring cardiac AdipoR2 and phosphorylation of Akt, STAT3 and eNOS in diabetic rats.
CONCLUSIONS/SIGNIFICANCE NAC and ALP synergistically restore myocardial APN and AdipoR2 mediated eNOS activation.
CONCLUSIONS/SIGNIFICANCE NAC and ALP synergistically restore myocardial APN and AdipoR2 mediated eNOS activation.
PloS one  •  2011  |  View Paper