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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Acetylcholine
supplement:
Vitamin E
Research Papers that Mention the Interaction
“… vitamin E diet … acetylcholine (58.2 ± 10.5 vitamin E, n = 7 vs 84.4 ± 5.3 % standard, p < 0.05), and the combined vitamin E plus … to sodium nitroprusside (48.5 ± 4.1 in vitamin E + C, n = 8 vs 75.6 ± 3.9 % standard; p < 0.01).”
Dietary antioxidant supplementation reduces lipid peroxidation but impairs vascular function in small mesenteric arteries of the streptozotocin-diabetic rat“Despite this ameliorating effect, vitamin E treatment caused an increase in contractile response to PE and a decrease in the relaxant response to Ach and SNP in arthritic rats.”
“ Vitamin E , a scavenger of free radicals, prevented the effects of SIN‐1 on ACh release.”
“ Vitamin E reversed impaired responses to ACh in the carotid but not the renal artery and also enhanced relaxant responses to A23187.”
“Dietary vitamin E partially reversed the impaired endothelium-dependent responses to acetylcholine associated with cholesterol feeding.”
“In raised-tone preparations, relaxant responses to acetylcholine were enhanced in rabbits fed cholesterol plus vitamin E , reversing the reduction in responses measured in preparations from cholesterol-fed rabbits.”
“Elevation of [Ca]in by intracellular injection from a microelectrode or by depolarizing pulses and application of 0.1 microM-0.1 mM vitamin E enhanced the acetylcholine-induced chloride current both in LP11 and RBc4 neurons.”
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