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Discover Supplement-Drug Interactions

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Last Updated: 4 years ago

Possible Interaction: Acetylcholine and Polypeptides

Research Papers that Mention the Interaction

These polypeptides inhibit acetylcholine release at neuromuscular junctions, thus causing muscle paralysis involving both somatic and autonomic innervation.
European Neurology  •  2009  |  View Paper
c) Acetylcholine stimulated, in a dose-dependent manner, the secretion of PP from the isolated perfused porcine pancreas, half-maximal effective dose being 0.19 muM; maximal PP output in response to 5 min stimulation was 228 pmol, range 140-342 pmol, n = 5.
The Journal of clinical investigation  •  1978  |  View Paper
Administration of acetylcholine resulted in an elevation of plasma PP , whereas epinephrine induced no increase.
The Tohoku journal of experimental medicine  •  1990  |  View Paper
Thus PP inhibits pancreatic enzyme secretion via presynaptic modulation of acetylcholine release.
The American journal of physiology  •  1987  |  View Paper
Two-dimensional gel … chromaffin cells to acetylcholine produced two types of effect … kinase activities affecting about 30 polypeptides ; activation of protein phosphatase activities resulting in the dephosphorylation of about 40 polypeptides, most of them … the exception of the alpha-subunit of pyruvate dehydrogenase and the 20.4 kilodaltons polypeptide.
Neuroscience  •  1986  |  View Paper