Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Acetylcholine and Manganese

supplement:

Manganese

Research Papers that Mention the Interaction

The secretion of acetylcholine to the conditioned medium was significantly increased after MN differentiation.
International journal of molecular sciences  •  2019  |  View Paper
Acetylcholine (ACh) modulates XII MN activity by promoting the release of glutamate from neurons that express nicotinic ACh receptors (nAChRs).
Journal of neurophysiology  •  2011  |  View Paper
The uptake of Mn was also stimulated by NE and ACh.
Journal of pharmacobio-dynamics  •  1990  |  View Paper
The contraction caused by acetylcholine in medium containing Ca was inhibited by Mn dose-dependently, whereas that caused by oxytocin was not affected by Mn.
General pharmacology  •  1983  |  View Paper
Abstract Manganese (2.2mM) blocked catecholamine (CA) secretion evoked by acetylcholine (ACh) in perfused bovine adrenals.
Life sciences  •  1981  |  View Paper
The antinociceptive effect of intracerebroventricularly administered acetylcholine as measured in the mouse tail-flick test was reduced by intracerebroventricularly injected calcium, magnesium and manganese.
The Journal of pharmacology and experimental therapeutics  •  1978  |  View Paper
The effect of ACh on amylase secretion can be mimicked by agents displacing membrane‐bound Ca (Mg, Ca, Mn).
The Journal of physiology  •  1976  |  View Paper
2 In the presence of manganese , the release of acetylcholine from the ileum was greatly increased.
British journal of pharmacology  •  1969  |  View Paper
Furthermore, Mn exposure reduced nicotinic acetylcholine receptor levels in the PFC, indicating that blunted acetylcholine signaling could contribute to impaired memory associated with intranasal manganese.
Toxicological research  •  2015  |  View Paper