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Last Updated: 3 months ago

Possible Interaction: Acetylcholine and Leucine



Research Papers that Mention the Interaction

In the presence of potassium, forskolin, and epinephrine, MG enhanced insulin secretion (P < 0.05), while when it was incubated with acetylcholine and leucine , MG resulted in a decrease of insulin secretion (P < 0.05).
International journal of endocrinology  •  2014  |  View Paper
In vitro studies revealed that SHR + L + S displayed a better relaxation response to acetylcholine than the untreated SHR and the SHR with monotherapy (P < 0.01).
The journal of sexual medicine  •  2007  |  View Paper
ISO (ISO-beta(1)/beta(2)-AR stimulation) increased I(Ca,L) and even though ISO releases NO, ACh prominently inhibited I(Ca, L).
When isoproterenol (ISO; 0.1 microM) plus the beta(2)-AR antagonist ICI 118,551 (ISO-beta(1)-AR … 0.1 microM fenoterol, a beta(2)-AR agonist (FEN-beta(2)-AR stimulation) increased I(Ca,L), ACh (1 microM) … I(Ca, L ) by -60 +/- 4 … -63 +/- 6 %, respectively.
The Journal of physiology  •  2002  |  View Paper
BAPTA-stimulated ICa L was inhibited by acetylcholine and by the cAMP-dependent protein kinase (PKA) blocker H-89.
Biophysical journal  •  1997  |  View Paper
Withdrawal of a 2-minute exposure to 1 mumol/L ACh elicited a rebound stimulation of ICa, L in both SAN (33 +/- 4%) and LAP (50 +/- 6%) cells above control.
Circulation research  •  1996  |  View Paper
High ACh concentrations were required to inhibit ICa, L only partially (31% inhibition at 300 microM).
The Journal of physiology  •  1996  |  View Paper
The depressing effect of ACh on ICa, L may occur via inhibition of the high basal adenylate cyclase activity leading to a decrease of cAMP-dependent protein kinase stimulation and thus to a dephosphorylation of calcium channels.
Pflügers Archiv  •  1993  |  View Paper
In hyperthyroid myocytes, acetylcholine (ACh) (1 μM) decreased ICa, L from −26.86±1.49 to −18.33±1.25 pA/pF (P<0.05), while in euthyroid myocytes ACh decreased ICa, L from −6.80±0.61 to −6.00±0.39 pA/pF (NS).
Pflügers Archiv  •  1992  |  View Paper