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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Acetylcholine and Hesperetin

supplement:

Hesperetin

Research Papers that Mention the Interaction

Hesperetin and diosmetin, but not hesperidin and diosmin, dose-dependently (10-100µM) and reversibly inhibited acetylcholine (1µM) and KCl (80mM) induced contractile activity.
European journal of pharmacology  •  2016  |  View Paper
Moreover, hesperetin (10(-5) M) enhanced endothelium-dependent relaxation induced by acetylcholine , but had no effect on endothelium-independent relaxation induced by sodium nitroprusside in isolated aortas from SHR.
Journal of nutritional science and vitaminology  •  2008  |  View Paper