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Last Updated: 3 years ago

Possible Interaction: Acetylcholine and Hesperetin

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drug:

Acetylcholine

supplement:

Hesperetin

Research Papers that Mention the Interaction

“ Hesperetin and diosmetin, but not hesperidin and diosmin, dose-dependently (10-100µM) and reversibly inhibited acetylcholine (1µM) and KCl (80mM) induced contractile activity.”

Antispasmodic effect of selected Citrus flavonoids on rat isolated jejunum specimens.

European journal of pharmacology • 2016 | View Paper

“Moreover, hesperetin (10(-5) M) enhanced endothelium-dependent relaxation induced by acetylcholine , but had no effect on endothelium-independent relaxation induced by sodium nitroprusside in isolated aortas from SHR.”

Short-term effects of glucosyl hesperidin and hesperetin on blood pressure and vascular endothelial function in spontaneously hypertensive rats.

Journal of nutritional science and vitaminology • 2008 | View Paper

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