supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 5 years ago
drug:
Acetylcholine
supplement:
Glutamate
Research Papers that Mention the Interaction
“It inhibits the sodium dependent uptake of L-glutamate and GABA and enhances the calcium-dependent release of acetylcholine.”
The effects of a purified toxic extract of Prymnesium patelliferum on transport of ions through the plasma membrane of synaptosomes.“An endogenous excitatory amino acid, L-glutamate , also elicited release of [3H]acetylcholine.”
“ ACh also potentiated responses to L-glutamate but not to kainate or quisqualate.”
“The duration of the responses to SP or ACh was significantly longer than the duration of the responses to Glu.”
“High concentrations (62 mM) of L-Glu increased the intrinsic activity (alpha) of ACh , indicating a postjunctional potentiation of ACh-induced contractions.”
“Out of 415 units examined 24.5% were directly excited by ACh, while in 9.4% ACh facilitated the excitatory effect of L-glutamate.”
ACETYLCHOLINE DEPRESSION OF CORTICAL NEURONS.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback