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Possible Interaction: Acetylcholine and Epinephrine

supplement:

Epinephrine

Research Papers that Mention the Interaction

Modulation of the vasoconstrictor or vasodilator tone of the skin blood vessels altered the magnitude of the BF response to electrical stimulation; epinephrine blocked the response and acetylcholine increased the response.
Medical science monitor : international medical journal of experimental and clinical research  •  2007  |  View Paper
However, during the washout of acetylcholine in the presence of epinephrine , the oscillatory potentials and aftercontractions were larger than before acetylcholine, and repetitive activity was often induced.
It is concluded that in human atrial fibers acetylcholine has inhibitory as well as excitatory effects that are exaggerated in the presence of epinephrine and are mediated by the activation of the muscarinic receptor.
The interaction between acetylcholine and epinephrine involves an antagonism at an intracellular level.
The American journal of physiology  •  1989  |  View Paper
Isoproterenol, epinephrine , and norepinephrine in that order of potency produced concentration-dependent inhibition of comparable responses to EFS and ACh.
Journal of applied physiology  •  1988  |  View Paper
On the other hand, a preparation relaxed by adrenaline contracts very little after additional application of acetylcholine.
Leber, Magen, Darm  •  1977  |  View Paper
Acetylcholine , present in mixtures with epinephrine or norepinephrine in ratios of 1:10 to 1:20, was effective in antagonizing the electrical effects of the latter.
The findings described here suggest a possible role of acetylcholine in the frog heart for reducing or preventing large electrical responses to epinephrine and norepinephrine.
The Journal of pharmacology and experimental therapeutics  •  1955  |  View Paper
The vacuolizing effects of acetylcholine are antagonized by atropine, scopolamine and Syntropan, as well as by epinephrine , ephedrine, phenylephrine and Paredrine.
The Journal of pharmacology and experimental therapeutics  •  1949  |  View Paper
Adrenaline inhibits the ability of these enzymes to hydrolyze acetylcholine.
The potentiation of acetylcholine activity by adrenaline is correlated with the inhibitory effect of adrenaline on cholinesterase.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1948  |  View Paper
Noradrenaline and adrenaline decreased the frequency of the spontaneous release of acetylcholine quanta.
Noradrenaline did not alter the quantal content of endplate potentials, while adrenaline suppressed the evoked release of acetylcholine.
Neuroscience  •  2019  |  View Paper
The combined administration of epinephrine and acetylcholine resulted in AF in all animals tested, which was invariably preceded by APBs.
Heart rhythm  •  2016  |  View Paper
RESULTS The injections of various doses of ad enaline de creased the mean regional blood flow and eruption rate dose-dependently, while those of ace tylcholine in creased the mean regional blood flow and eruption rate dose-dependently.
Significant correlations (p<0.001) were obtained between the maximum and minimum values in the regional blood flow and in the eruption rate following injections of various doses of adrenaline and acetylcholine.
Archives of oral biology  •  2006  |  View Paper
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