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European journal of pharmacology • 1991 | View Paper
“But high concentration of emodin could reduce even completely antagonize the effect of Ach.”
“ Emodin with appropriate concentration (14.8 mumol/L) strengthened the effect of acetylcholine (Ach) on the isolated ileum and large intestine of guinea-pigs (P < 0.05 and P < 0.01).”