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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Acetylcholine and Dietary Fiber

Research Papers that Mention the Interaction

We can recognize two associated, but separable effects of acetylcholine on skeletal muscle, depolarization of the end-plate producing conducted responses of the muscle, and a more intense depolarization, spreading far beyond the end-plate, producing neuromuscular block and conduction block in the length of the fibre.
Proceedings of the Royal Society of London. Series B - Biological Sciences  •  1950  |  View Paper
Acetylcholine significantly inhibited tone-induced responses of a large proportion of the fibres tested.
Experimental Brain Research  •  2004  |  View Paper
The depolarization elicited by iontophoretically applied acetylcholine ACh ) was reversibly decreased by 20–60% when muscle fibres were exposed to 1–5×10−7 M TPA.
Pflügers Archiv  •  2004  |  View Paper
Secondly, in contrast to the intracortical connection, some group(s) of fibres , possibly thalamocortical afferents that arise from white matter and terminate in the middle cortical layers are suppressed much less by ACh.
The European journal of neuroscience  •  1999  |  View Paper
Acetylcholine decreased automaticity in normal fibres only at high concentration (100 microM).
Cardiovascular research  •  1990  |  View Paper
In both types of cultures, sensitivity to ionophoretically applied acetylcholine decreased during the period when fibres were growing rapidly and then increased.
The Journal of physiology  •  1985  |  View Paper
Since the only known action of the post-synaptic blocking fraction of this venom is due … its affinity to acetylcholine receptors, the results suggest that the spread in the sensitivity of muscle fibres to acetylcholine and their ability to accept a foreign nerve is a consequence of neuromuscular blockade.
Quarterly journal of experimental physiology and cognate medical sciences  •  1978  |  View Paper
IT is known that depolarization of the postsynaptic membrane of muscle fibres caused by acetylcholine gradually decreases as a result of its prolonged action: after some time the membrane protential may attain its initial level despite the presence of acetylcholine.
Nature  •  1970  |  View Paper
It thus seemed likely that externally applied acetylcholine could alter the electrophysiological properties of mammalian C fibres , but with the techniques then used no definite conclusions could be reached.
The Journal of physiology  •  1960  |  View Paper
Further they, and later Brown & Gray (1948), also observed that acetylcholine aroused impulses in some of these intestinal fibres.
The Journal of physiology  •  1957  |  View Paper