Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Acetylcholine and Citicholine

supplement:

Citicholine

Research Papers that Mention the Interaction

Other phospholipids involved in choline biosynthetic pathways such as CDP-choline , choline alphoscerate and phosphatidylserine clearly enhanced ACh availability or release and provided a modest improvement of cognitive dysfunction in AD, these effects being more pronounced with choline alphoscerate.
Mechanisms of Ageing and Development  •  2001  |  View Paper
administration of CDP-choline can significantly increase extracellular levels of ACh in dorsal hippocampus and neocortex in normal, awake, freely moving rats.
administration of CDP-choline increases acetylcholine (ACh) release in the dorsal hippocampus and neocortex.
Journal of neurotrauma  •  1997  |  View Paper
In the ICB the infusion of CDP-choline for 30 min significantly shifted the dose-response curve to ACh to the left, potentiating the relaxation.
General pharmacology  •  1994  |  View Paper
For example, cytidine 5′-diphosphocholine (CDP-choline), a metabolite of choline, has been reported to aid in neural repair in the central and peripheral nervous systems as well as increase levels of acetylcholine (Arenth et al., 2011).
Neural regeneration research  •  2017  |  View Paper