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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Acetylcholine and Choline Chloride

Research Papers that Mention the Interaction

Precursorloading with choline chloride may increase brain acetylcholine levels and central cholinergic activity.
Biological psychiatry  •  1978  |  View Paper
Eight elderly patients with mild memory impairment were given choline chloride , a drug that increases brain acetylcholine concentrations.
The American journal of psychiatry  •  1979  |  View Paper
The ACh produced from the transduced fibroblasts was found to be enhanced by increasing amounts of choline chloride in the culture media.
Journal of neurochemistry  •  1993  |  View Paper
Moreover, intra- and extracellular levels of ACh could be increased by adding exogenous choline chloride.
Journal of neurochemistry  •  1992  |  View Paper
We found that … potassium-depolarized ACh release from rat … significantly accelerated when choline chloride was added to the incubation medium at concentrations of either 60 or 100 microM. The ACh content of … minces was reduced by prolonged depolarization; this depletion was prevented by incubating minces with choline (100 microM).
Brain Research  •  1982  |  View Paper
Abstract Administration of choline chloride (200 μmoles/kg) intravenously to guinea pigs caused an increase in the concentrations of choline and acetylcholine in adrenals, heart, kidneys, lungs, and liver within 2 min.
Life sciences  •  1974  |  View Paper