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Last Updated: 3 years ago

Possible Interaction: Acetylcholine and Agmatine

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drug:

Acetylcholine

supplement:

Agmatine

Research Papers that Mention the Interaction

“Furthermore AGM prevented the impaired aortic contraction to KCl and phenylephrine (PE) and endothelium-dependent relaxation to acetylcholine (ACh) without affecting endothelium-independent relaxation to sodium nitroprusside (SNP).”

The inhibition of inducible nitric oxide synthase and oxidative stress by agmatine attenuates vascular dysfunction in rat acute endotoxemic model.

Environmental toxicology and pharmacology • 2017 | View Paper

“In cells voltage-clamped at -80 mV, the intermittent application of acetylcholine pulses elicited whole-cell inward currents (I(ACh)) that were blocked 63% by 1 mM agmatine.”

Blockade by agmatine of catecholamine release from chromaffin cells is unrelated to imidazoline receptors.

European journal of pharmacology • 2001 | View Paper

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