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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Acetylcarnitine
drug:
Paclitaxel
Research Papers that Mention the Interaction
“RESULTS AL co treatment was able to significantly reduce the neurotoxicity of both cisplatin and pac litaxel in rat models, and this effect was correlated with a modulation of the plasma levels of NGF in the cisplatin-treated animals.”
Paclitaxel and Cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine.“The incidence and severity of peripheral sensory neuropathy associated with taxane-agents such as paclitaxel can be reduced with vitamin E, glutamine, and acetyl-L-carnitine.”
“Prophylactic treatment with acetyl-L-carnitine (ALCAR) prevents the neuropathic pain syndrome that is evoked by the chemotherapeutic agent, paclitaxel.”
Prevention of paclitaxel-evoked painful peripheral neuropathy by acetyl-l-carnitine: Effects on axonal mitochondria, sensory nerve fiber terminal arbors, and cutaneous Langerhans cells
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