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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Acetylcarnitine and Nifedipine

Research Papers that Mention the Interaction

Here, we tested whether toxicities of nifedipine , a dihydropyridine CCB used to treat hypertension, can also be mitigated by co‐treatment with ALCAR.
In the zebrafish embryos at three different developmental stages, nifedipine induced developmental toxicity with pericardial sac edema in a dose‐dependent manner, which were surprisingly exacerbated with ALCAR co‐treatment.
To the best of our knowledge, these studies for the first time show that nifedipine and the dietary supplement ALCAR together induce adverse effects while providing evidence on the therapeutic efficacy of subanesthetic doses of ketamine against nifedipine toxicity in vivo.
Journal of applied toxicology : JAT  •  2019  |  View Paper
The current study was carried out to investigate the anti-cataractogenic effect of single and combined treatment with acetyl-l-carnitine and nifedipine in sodium selenite-induced cataract.
European journal of pharmacology  •  2014  |  View Paper