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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Acetylcarnitine and Doxorubicin Hydrochloride

Research Papers that Mention the Interaction

RESULTS DO si gnificantly decreased the EF values, whereas ALC AR di d not.
Archives of medical research  •  2016  |  View Paper
Also ADR induced concentration-dependent inhibition of CPT I which is parallel to the inhibition of its substrate palmitoyl-CoA. In rat heart slices, ADR induced a significant (65%) decrease in adenosine triphosphate (ATP) and this effect is reduced to 17% only by PLC.
In isolated rat heart mitochondria, ADR produced concentration-dependent inhibition of both palmitoyl-CoA and palmitoyl-carnitine oxidation, while PLC caused a more than 2.5-fold increase in both substrates.
Pharmacological research  •  2000  |  View Paper