“ Acetyl-L-carnitine augmentation of CLZ significantly reduced only PANSS domains “positive” (P = 0.049); at end point, only 2 subjects (22.2% of the completers) reached a minimal improvement (25% reduction in PANSS total score).”
“ConclusionsThe findings provide preliminary evidence that ALC added to ongoing CLZ treatment appeared to be ineffective to improve symptoms in schizophrenia patients who have failed to respond sufficiently to CLZ.”