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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Acetylcarnitine
drug:
Atropine
Research Papers that Mention the Interaction
“ Atropine blocked the increase in firing rate induced by L-carnitine and L-acetylcarnitine , thus suggesting for both of them a muscarinic activity.”
Activity of L-carnitine and L-acetylcarnitine on cholinoceptive neocortical neurons of the rat in vivo“The stimulatory effect of ALCAR on the release of amino acids in the striatum was inhibited by the muscarinic antagonist atropine , but was not inhibited by the nicotinic antagonist mecamylamine.”
“The antinociception produced by ALCAR was prevented by the unselective muscarinic antagonist atropine , the M(1) selective antagonists pirenzepine and S-(-)-ET126, and by the choline uptake inhibitor hemicholinium-3 (HC-3).”
“The effects of L-acetyl carnitine could be depressed by the simultaneous administration of atropine sulfate.”
“Intracerebral injection of L-acetylcarnitine in rats induced interictal and ictal epileptic phenomena with immediate onset, lasting up to 4 h. Pretreatment with systemic atropine prevents all epileptiform phenomena.”
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