“ Nimesulide and SC‐236 decreased the enhanced colonic eicosanoid generation in acetic acid and iodoacetamideinduced colitis, and, in iodoacetamide‐treated rats, nimesulide also decreased the elevated serum TNF‐&agr; and IL‐1&bgr; levels.”
“Results Nimesulide significantly decreased the extent of colitis induced by acetic acid.”